Heart Attack Test

  by  |  February 20th, 2009  |  Published in All, Featured, Health

 |  Stumble |  Share on Facebook |  Tweet This | 

Researchers say they have a test that can tell if you’re having a heart attack in just minutes rather than the current test that takes hours. And as this ScienCentral News video explains, they discovered it by studying patients who need heart attacks.

[If you cannot see the flash video below, you can click here for a high quality mp4 video.]

Interviewee: Robert Gerszten, Massachusetts General Hospital
Produced by Joyce Gramza– Edited by James Eagan
Copyright © ScienCentral, Inc

Quicker Blood Test Means Quicker Treatment

When cardiologist Mike Fifer happened to mention to his colleague Rob Gerszten that he was admitting a patient to Mass General’s coronary care unit for a planned heart attack, "a light went off for both of us," Gerszten recalls.

They realized it was the perfect opportunity to search for new blood markers of heart attack. Heart attacks change levels of chemicals in the blood, but current tests look for changes that take hours to happen. Gerszten and Fifer wanted to find chemical changes that occur immediately.

Also on ScienCentral

This is most important because all of our treatments for heart injury work best very early after the injury has started," Gerszten says.

Needing a Heart Attack

The researchers and their team studied patients with a rare condition called hypertrophic cardiomyopathy.

"In this unique situation, patients actually have too much heart muscle," explains Gerszten. "We perform a planned heart attack to minimize the excess heart muscle, and only in this unique scenario after the heart attack do the patients actually improve."

The team was able to take blood samples before, during and after the planned heart attacks. Collaborating with the Broad Institute of MIT and Harvard, where Gerszten is an senior associate member, they used a technique called high performance liquid chromatography-mass spectrometry (HPLC-MS) to identify and compare the levels of hundreds of different chemicals in the blood samples.

"Within 10 minutes of a heart attack we found approximately 10 new changes in the blood that had previously never been described," Gerszten says.

But since this group of patients each served as their own "control group," the researchers needed to find out if their findings would generalize to the rest of us if we have an unplanned heart attack.

So, as they wrote in the Journal of Clinical Investigation, the team then studied blood samples of heart attack patients coming into the emergency room to see if they would show the same chemical signature.

"And indeed, these changes that we saw in a planned heart attack were also seen in patients having spontaneous heart attacks as well," says Gerszten.
"This is early proof of principle that these tools will work," he adds. "Obviously, we need to test them in large groups of subjects now– not just tens or hundreds of subjects, but in thousands of subjects coming into the emergency department to see if they hold up in these larger studies."

Win-Win Situation

It’s also possible that the research may lead to better treatments. "I think that these changes that we found in the blood also have important implications for our therapy for heart attacks as well," Gerszten says. "We clearly see abnormal changes in certain biochemical pathways in the heart. That suggests targets for therapeutic intervention."

He hopes in a few years this early detection will lead to widespread treatment of heart attacks, not in hours, but in minutes.

"We’re very excited that we’ve identified new chemical changes in the blood that indicate the earliest changes after a heart attack," he says. "But the subjects have also benefited from this procedure, so it’s really a win-win situation."

This research was published in the Journal of Clinical Investigation, online publication October 2008, and was funded by: NIH, the Donald W. Reynolds Foundation, Fondation Leducq, Heart Failure Society of America, American Heart Association, the Harvard/MIT Clinical Investigator Training Program, the Broad Institute Scientific Planning Allocation of Resources Committee, the Sarnoff Cardiovascular Research Foundation and the Keck Foundation.

Elsewhere on the Web:

"Metabolomics: What’s Happening Downstream of DNA" from Environmental Health Perspectives

American Heart Association

National Heart, Lung & Blood Institute

 |  Stumble |  Share on Facebook |  Tweet This | 


  1. jokeswork says:

    April 3rd, 2009 at 2:52 am (#)

    I’m addicted to your website, even if I don’t understand a single word of it.

  2. Angel Baker says:

    May 19th, 2010 at 9:15 pm (#)

    A close friend of mine died of a Heart Attack, his heart condition is caused by him being so obese.*~:

  3. Avery Nelson says:

    June 10th, 2010 at 11:53 pm (#)

    Heart attack could be prevented with exercise, diet and some food supplements like CoQ10.;:*

  4. Eyelid Surgery : says:

    October 23rd, 2010 at 11:15 am (#)

    heart attack is the number 1 killer of middle-aged and old-aged people these days~:*

  5. Sublingual Vitamins %0B says:

    December 16th, 2010 at 2:27 am (#)

    heart attack is very common these days, it is because of a high fat diet and lack of exercise **`

  6. Jae Vicario says:

    September 9th, 2011 at 6:34 pm (#)

    Heya just wanted to give you a brief heads up and let you know a few of the pictures aren’t loading correctly. I’m not sure why but I think its a linking issue. I’ve tried it in two different internet browsers and both show the same outcome.

  7. NYC Bed Bug Exterminator says:

    September 18th, 2011 at 3:03 pm (#)

    Very good blog! Do you have any tips and hints for aspiring writers? I’m planning to start my own site soon but I’m a little lost on everything. Would you suggest starting with a free platform like WordPress or go for a paid option? There are so many options out there that I’m totally confused .. Any suggestions? Many thanks!

  8. Coach handbags outlet sale says:

    September 23rd, 2011 at 4:23 pm (#)

    People really lend a hand to make certainly threads I will talk about. Be the first time We stopped at your internet-site web page thus much? I really blown away together with the investigation you have made to create this specific real create unbelievable. Superb career!

  9. opakowania tekturowe says:

    November 26th, 2011 at 4:20 am (#)

    I don’t commonly comment but I gotta say regards for the post on this great one : D.

  10. christian louboutin says:

    January 14th, 2012 at 10:40 am (#)

    Utterly indited content , Really enjoyed studying.

  11. lolo says:

    March 15th, 2012 at 10:35 pm (#)

    This site is actually fascinating i’m searching for is there the other examples? but anyway thanks a great deal as a result of I found that i was probing for.

  12. Darrel Neault says:

    March 20th, 2012 at 9:46 am (#)

    I don’t ordinarily comment but I gotta say regards for the post on this one : D.

  13. Eldridge Rohr says:

    March 21st, 2012 at 9:25 am (#)

    This website is my aspiration , very excellent style and design and perfect written content .

  14. Russel Tomjack says:

    April 2nd, 2012 at 8:20 am (#)

    I believe this site holds some real fantastic information for everyone : D.

  15. Holli Hagadone says:

    April 4th, 2012 at 8:54 am (#)

    I am delighted that I found this website , precisely the right information that I was searching for! .

  16. Jesusa Barck says:

    April 10th, 2012 at 12:04 pm (#)

    betting bonus bettingbonuses.biz

  17. wulkanizacja katowice says:

    April 27th, 2012 at 9:27 am (#)

    As I website possessor I conceive the articles here is rattling excellent , thankyou for your efforts.

  18. Brain Waddy says:

    July 21st, 2012 at 12:12 am (#)

    I am glad to be one of many visitors on this outstanding web site (:, regards for putting up.

  19. Eric Jutte says:

    July 23rd, 2012 at 10:30 pm (#)

    Heart attack can be prevented by following daily exercise routine and also with the use of protective health supplements. ;.*.`

    Thanks again

  20. Alphonso Bednarz says:

    July 27th, 2012 at 8:51 am (#)

    Yay google is my world beater aided me to find this outstanding website ! .

  21. Ora Halgas says:

    July 30th, 2012 at 8:27 am (#)

    Yay google is my queen helped me to find this great website ! .

  22. book flights ticket says:

    March 22nd, 2013 at 3:35 pm (#)

    Howdy! I realize this is sort of off-topic but I had to ask. Does running a well-established blog such as yours require a lot of work? I am completely new to operating a blog but I do write in my diary every day. I’d like to start a blog so I can share my personal experience and views online. Please let me know if you have any recommendations or tips for brand new aspiring blog owners. Thankyou!| book flights ticket http://www.funtraveldeals.com/book-flights/

  23. agate cameos bangle says:

    March 22nd, 2013 at 4:06 pm (#)

    Hello there, just became aware of your blog through Google, and found that it is truly informative. I’m gonna watch out for brussels. I will be grateful if you continue this in future. A lot of people will be benefited from your writing. Cheers!| agate cameos bangle http://www.goldmemoriesforever.com

  24. papaka says:

    March 22nd, 2013 at 4:31 pm (#)

    Excellent site you have here but I was wanting to know if you knew of any user discussion forums that cover the same topics talked about here? I’d really love to be a part of community where I can get suggestions from other knowledgeable individuals that share the same interest. If you have any recommendations, please let me know. Thanks!| papaka http://www.takeload.com

  25. CustomsbrokerageinKeny says:

    March 23rd, 2013 at 8:47 am (#)

    Today, I went to the beachfront with my kids. I found a sea shell and gave it to my 4 year old daughter and said “You can hear the ocean if you put this to your ear.” She placed the shell to her ear and screamed. There was a hermit crab inside and it pinched her ear. She never wants to go back! LoL I know this is entirely off topic but I had to tell someone!| Customs brokerage in Kenya http://mj-resources.net

  26. walmartgarciniacambogi says:

    March 23rd, 2013 at 9:01 am (#)

    Hi there, after reading this amazing article i am as well happy to share my know-how here with friends.| walmart garcinia cambogia http://www.pure-garcinia-cambogia.org

  27. HochzeitsfotografMünch says:

    March 23rd, 2013 at 10:06 am (#)

    Good day! Would you mind if I share your blog with my myspace group? There’s a lot of people that I think would really enjoy your content. Please let me know. Cheers| Hochzeitsfotograf München http://www.fotostudioaugenblicke.de

  28. AlternativestoGooglese says:

    March 24th, 2013 at 1:00 pm (#)

    Many thanks for scripting this remarkable post..Liked your content. Make sure you do hold writing Alternatives to Google search engine http://asdasghdsdfs5hf.com

  29. copy reading exercises journalism says:

    April 26th, 2013 at 10:11 am (#)

    An unschooling atmosphere is one other excursions for a fun filled
    Speed Learning clock time. aside from that, it can around them isspeed learning, and they are potential to pay aid
    and work on gruelling due to thisstructure. Sean’s parents wanted him to be in the is lovely.

  30. christian louboutin black pumps says:

    April 28th, 2013 at 5:25 am (#)

    I am actually thankful to the owner of this website who has
    shared this fantastic piece of writing at here.

  31. Francis Stemler says:

    June 13th, 2013 at 3:01 pm (#)

    I might move to Hawaii and after that travel the globe.

  32. the pirate bay says:

    August 6th, 2013 at 8:34 pm (#)

    As such, it mustn’t be too difficult to spend some time developing a database of tables similar to what is suggested at where they’ve
    got provided a sample database spec to be used in a hotel reservation
    application. By the process, you happen to be reinforcing that negativity and
    attracting to yourself MORE. The vulnerability has apparently been fixed since interview with Russo took place, and usernames are again safe and secure.

  33. fundamentals of project management pdf says:

    January 16th, 2014 at 5:42 am (#)

    I used to be proposed this amazing site via my relation. I’m not beneficial whether or not it post is authored by your pet because nobody know this sort of specific concerning my personal trouble. You are astounding! Thank you so much!

  34. extreme bo staff says:

    September 22nd, 2014 at 4:35 pm (#)

    Gentle girl with glasses, or earrings to curb their love of fashion this season, because glasses
    have been occupied in a large area of the face, and only small
    earrings to wear as a decoration, can become the size of
    scattered, do not have fun. He is an honest line hugging the Teenage Mutant
    Ninja Turtles costume accessories for sale and to the other
    side of the combination. Get a discount by signing up for all three seminars INCLUDING the weapons for only $99.

    my blog post extreme bo staff

  35. lawn fertilizer says:

    October 16th, 2014 at 9:57 pm (#)

    Keep this going please, great job!

    Feel free to surf tto my weblog: lawn fertilizer

  36. Pirate Bay says:

    January 29th, 2015 at 8:31 pm (#)

    They are classified into free, mainstream and paid membership sites.
    Ms windows and Mac OS X are a few the systems where utorrent might be installed.
    The features available with these kinds of companies are a large amount of disk space, unlimited traffic approximately 100mbit, privacy, a number of active
    torrents and not to mention FTP access.

  37. www.mitico.ch says:

    February 23rd, 2015 at 11:20 pm (#)

    s not something you can expect the majority in the general public to afford,
    thus, for Forex Strikers, the lowest investment of only $500-$1000 per instrument (currency pair) is required.
    This is simply precaution how the material isnt attached with a cookie inside your internet cache.
    A variety of musicians have been not able to sustain themselves and
    so they have opted to doing other ventures of the side.

  38. The Pirate Bay says:

    March 17th, 2015 at 3:41 am (#)

    Net Turtle allows you to download anything from your Internet,
    regardless of whether there is a limit in your Black – Berry for
    file size. Bahya kumbhaka is the state the location where the yogi surrenders his very
    self , within the form of his breath, towards
    the lord and merges with universal breath it is the noblest way of surrender, since the yogi’s
    identity is totally merged with all the Lord. The reason for this is because fiber optic cables are made-up of conducting light material and
    therefore transmit the light from the end to an alternative

  39. File Search Engine says:

    January 16th, 2019 at 4:42 pm (#)

    Just want to say your article is as astonishing. The clarity in your post is simply spectacular and i can assume you’re an expert
    on this subject. Fine with your permission let me to grab your
    feed to keep up to date with forthcoming post.
    Thanks a million and please keep up the enjoyable work.

Leave a Response


Clicky Web Analytics