Bad Belly Fat

  by  |  May 13th, 2008  |  Published in All, Health


 |  Stumble |  Share on Facebook |  Tweet This | 

Scientists are finding more about how that bulge around your belly is more harmful than the pounds you may have elsewhere on your body. As this ScienCentral News video reports, belly fat may cause blockages in the arteries, and the finding could lead to better drugs to protect against heart disease.

[If you cannot see the You Tube video below, you can click here for a hi-res mp4 video or here for a quicktime video.]

Interviewee: Daniel Eitzman, University of Michigan
Length: 1 min 27 sec
Produced by Joyce Gramza
Edited by Chris Bergendorff
Copyright © ScienCentral, Inc., with additional footage
from the University of Michigan.

Apple or Pear?

Not all fat is created equal. Accumulating most of your fat around your waistline, or having what’s often called an “apple shape,” is known to be more dangerous than storing fat around your hips and buttocks, known as having a “pear shape.”

That’s because they are actually two different kinds of fat. The fat in your abdomen tends to be visceral fat, which builds up around your organs, as opposed to subcutaneous fat, or fat under the skin. Visceral fat is strongly linked to metabolic syndrome, the insulin resistance that increases our risk of heart disease, cancer, and all sorts of diseases associated with aging.

Obesity researcher Daniel Eitzman says that makes it tricky to study the effects of the fat itself.

“When we look at obese humans or animal models of obesity, they develop other well-established risk factors such as diabetes or elevated blood cholesterol that can affect heart disease,” he explains. “So it’s difficult to tease apart the specific role of the belly fat from these other associated risk factors that are triggered by obesity.”

But in a new study in mice, Eitzman and his team at the University of Michigan were able to control for those factors.

“This study demonstrates a direct effect of belly fat on, on heart disease, and this effect occurs without changes in diabetes or blood cholesterol,” Eitzman says.

The study come came about serendipitously, he says. The researchers were studying appetite hormones produced by fat by transplanting different kinds of fat from other mice into non-obese mice.

When they looked at the transplants several months later, they found fat cells had become inflamed in mice that received belly fat.

“It was very interesting to us that the inflammation in these transplanted fat pads looked very similar to the type of inflammation that is seen in humans with obesity,” Eitzman explains.

That led them to do fat transplantations in mice that are bred to have no diabetes or high cholesterol but are prone to heart artery blockages. Again, the researchers saw inflammation around fat cells only in the belly fat group.

“Mice that received this inflammatory fat developed a greatly accelerated amount of blockage in the arteries compared with other mice that received the same operation with no fat implantation, or with mice that received a different type of fat, subcutaneous fat,” says Eitzman.

And as they wrote in the journal Circulation they didn’t stop there.

“The next question we wanted to address was: ‘Is there any way we can reduce the fat inflammation, and if we do reduce the fat inflammation, will this have a beneficial effect on heart disease?’” Eitzman says.

They gave the mice a drug called pioglitazone, which is used in treating type 2 diabetes.

“The reason we used it is, it has a particular effect on what the fat cell secretes, and this drug also affects inflammation,” Eitzman says. “So when we treated mice that received the fat transplantation with pioglitazone, this reduced the inflammation in the fat and also reduced the effect of this type of fat on the blockages in the arteries.”

“The jury is still out on the potential cardiovascular benefits of pioglitazone, but it’s possible that this drug, or drugs like this drug, may be particularly effective in reducing the cardiovascular risk associated with inflammatory fat,” he says.

But Eitzman thinks this line of research will lead to better, more specific drugs to protect against the effects of belly fat.

“The problem with pioglitazone is, while it is effective at reducing inflammation, it affects many other tissues, and many other molecules, and so there may be improved therapies if we gain a better understanding of what these specific factors are,” he says.

In the meantime, Eitzman says it’s yet another reason to get rid of that gut.

“I’ve always told patients to lose weight in attempt to reduce their risk for heart disease, but this study shows that we may even may need to be more aggressive,” he says.

“Even if the diabetes has been taken care of and the blood lipids look okay, if they still carry this excessive belly fat, there may be yet another reason to lose weight, and the weight loss may reduce inflammatory characteristics of this belly fat.”

Indeed, belly fat is dangerous even if you don’t qualify as obese. “The results of these studies may not only apply to the obese population,” says Eitzman.

“There are people who don’t meet criteria for obesity that still have excess belly fat, and these patients are likely also at increased risk for heart disease. There also may be obese patients with a pear-shape that are not at the same risk that other people are that carry this fat centrally,” he says. “Identifying what these specific factors are that mediate the risk of the different types of fat may be very helpful in designing therapeutic strategies to reduce the vascular risk associated with obesity.”

This research was published in Circulation, January 2008 and funded by the National Institutes of Health.


 |  Stumble |  Share on Facebook |  Tweet This | 


Responses

  1. Darnell Watt says:

    October 24th, 2008 at 10:40 pm (#)

    Great information on belly fat

  2. Gavin says:

    November 19th, 2008 at 4:25 pm (#)

    Pretty neat stuff! Belly fat is very dangerous so make sure to be active in your day to day life. Proper nutrition and activity is vital!

  3. Wayne says:

    March 3rd, 2009 at 9:22 am (#)

    Too much belly fat can cost you not only your health but also lower your self-esteem.

    Get unbiased belly fat loss reviews here.

  4. Dylan White says:

    June 21st, 2010 at 10:46 am (#)

    i used to buy those expensive fat pads on malls.~’~

  5. Sophie Sanders says:

    July 18th, 2010 at 11:37 pm (#)

    i am looking for cheap fat pads, can someone tell me a store that sells them cheap?**;

  6. Sydney Collins says:

    July 19th, 2010 at 2:16 am (#)

    i am looking for cheap fat pads, can someone tell me a store that sells them cheap?***

  7. Leah Anderson says:

    August 31st, 2010 at 1:10 am (#)

    my niece sometimes uses Fat Pads ::*

  8. Fish Oil : says:

    October 22nd, 2010 at 11:42 am (#)

    fat pads are not great for the body, i really want to lose them,,”

  9. Anti Aging Products %0B says:

    December 13th, 2010 at 12:16 am (#)

    oh i just hate the fat pads that i got, my fat pad is just genetics so i can’t do anything about it .’”

  10. communication skills training says:

    August 8th, 2011 at 3:56 pm (#)

    Awesome job on this post.

  11. Andrea Treuter says:

    September 1st, 2011 at 2:32 pm (#)

    My extended internet lookup has at the end of the day been honored with excellent content to talk about with my classmates and friends.

  12. Ellsworth Macphail says:

    September 7th, 2011 at 11:06 am (#)

    I am a website crazed man or women and that i desire to go through trendy blog site similar to the one you have

  13. sex toys says:

    September 12th, 2011 at 2:06 am (#)

    you’re really a good webmaster. The website loading speed is amazing. It seems that you are doing any unique trick. Also, The contents are masterpiece. you’ve done a wonderful job on this topic!

  14. ugg boots us says:

    October 10th, 2011 at 6:49 pm (#)

    This is the second pair of uggs I purchased in the last two years! My daughter wore them almost everyday right up until the spring. These boots look good with both pants and skirts and come in a number of colors. It is worth it to waterproof them if you intend to wear them on rainy or slushy days. Spots can be easily removed with a little white vinager and cold water!

  15. fajnestrony says:

    October 28th, 2011 at 8:19 am (#)

    I as well think so , perfectly indited post! .

  16. mercurial vapors says:

    November 8th, 2011 at 5:04 am (#)

    You made some first rate factors there. I appeared on the internet for the problem and located most people will go along with along with your website.

  17. Lavone Longstreth says:

    November 10th, 2011 at 5:44 am (#)

    Very interesting publish, searching to determine much more publish similar to this.

  18. pacquiao vs marquez live streaming says:

    November 10th, 2011 at 6:05 pm (#)

    Once I initially commented I clicked the -Notify me when new feedback are added- checkbox and now every time a remark is added I get 4 emails with the identical comment. Is there any method you possibly can remove me from that service? Thanks!

  19. Walter Colon says:

    November 17th, 2011 at 10:30 am (#)

    Merely wanna comment that you have a very decent site, I like the design it really stands out.

  20. Jesus Woods says:

    November 17th, 2011 at 6:54 pm (#)

    With havin so much written content do you ever run into any problems of plagorism or copyright violation? My site has a lot of unique content I’ve either written myself or outsourced but it appears a lot of it is popping it up all over the internet without my authorization. Do you know any methods to help prevent content from being ripped off? I’d definitely appreciate it.

  21. opakowania kartonowe says:

    November 26th, 2011 at 4:03 am (#)

    I don’t ordinarily comment but I gotta state regards for the post on this perfect one : D.

  22. Troy Polamalu fan says:

    December 6th, 2011 at 12:16 pm (#)

    Thanks a million and please carry on the enjoyable work. Its like you read my mind! You appear to know so much about this, like you wrote the book in it or something. I think that you can do with a few pics to drive the message home a little bit, but other than that, this is great blog.

  23. ugg boots on sale in uk says:

    December 26th, 2011 at 7:12 am (#)

    What would most of us do devoid of the magnificent thoughts you share on this website? Who comes with the tolerance to deal with essential topics in the interest of common readers like me? My spouse and i and my pals are very fortunate to have your website among the ones we often visit. Hopefully you know how much we enjoy your efforts! Best wishes from us all.

  24. Why Motorists That Compare Car Breakdown Cover Are Better Off in the Long Term says:

    January 5th, 2012 at 1:18 am (#)

    I am now not positive where you are getting your info, but great topic. I needs to spend a while learning much more or working out more. Thanks for excellent information I used to be on the lookout for this info for my mission.

  25. christian louboutin says:

    January 14th, 2012 at 9:05 am (#)

    I got what you mean , thankyou for posting .Woh I am thankful to find this website through google.

  26. fast and succesful diet says:

    March 11th, 2012 at 2:44 am (#)

    As I website possessor I believe the content material here is very excellent , thankyou for your efforts.

  27. Don Janos says:

    April 4th, 2012 at 8:36 am (#)

    Glad to be one of several visitants on this amazing internet site : D.

  28. paul smith belts says:

    April 7th, 2012 at 9:08 pm (#)

    Think about taking a look at us. Thanks to the blog owner for the excellent post.

  29. Maile Mangus says:

    April 11th, 2012 at 10:13 am (#)

    Wonderful blog post. I definitely take pleasure in this particular blog. Stick with it!

  30. Heidi Shobe says:

    April 13th, 2012 at 10:08 am (#)

    Superb post. I am currently facing some of these issues as well.

  31. bałtyk morze says:

    April 16th, 2012 at 9:09 am (#)

    Its good as your other posts : D, regards for posting .

  32. planety says:

    May 14th, 2012 at 10:35 am (#)

    Just wanna input on few general things, The website layout is perfect, the articles is very superb : D.

  33. Elfreda Ridens says:

    July 21st, 2012 at 12:00 am (#)

    I appreciate your piece of work, appreciate it for all the great articles .

  34. Jeffie Elumbaugh says:

    July 27th, 2012 at 8:37 am (#)

    As I website possessor I believe the subject material here is rattling fantastic , regards for your efforts.

  35. Filiberto Motl says:

    July 30th, 2012 at 8:10 am (#)

    I likewise conceive therefore , perfectly written post! .

  36. Codi Ivey says:

    August 1st, 2012 at 9:11 am (#)

    I went over this internet site and I believe you have a lot of fantastic information, bookmarked (:.

  37. Lux Prestige says:

    August 29th, 2012 at 6:53 am (#)

    Компания Люкс Престиж является лидирующей в сфере продаж спальных комплектов для комфортного и здорового сна. Квалифицированные специалисты, богатый опыт работы, делают нас лидерами в своем деле. Наши сотрудники Lux Prestige жизнерадостные и уверенные в себе люди. Мы помогаем выспатся нашим клиентам! :) Наши клиенты доверяют и любят нас!

  38. Kattie Rempe says:

    September 24th, 2012 at 1:53 pm (#)

    I had exactly the same deal recently (the buyer was during the Mexican Navy this time) and it screwed up the sale…

  39. clouds and sheep apk says:

    October 11th, 2012 at 8:24 pm (#)

    Great post at Bad Belly Fat | ScienCentral | Science Videos | Science News. I was checking continuously this blog and I’m impressed! Extremely useful information particularly the last part :) I care for such information much. I was looking for this certain info for a very long time. Thank you and good luck.

  40. Teachers Day Quotes In English says:

    October 17th, 2012 at 8:21 pm (#)

    Wow, fantastic blog layout! How long have you been blogging for? you made blogging look easy. The overall look of your website is wonderful, as well as the content!. Thanks For Your article about Bad Belly Fat | ScienCentral | Science Videos | Science News .

  41. Robbie Oyston says:

    January 15th, 2013 at 5:06 pm (#)

    Here’s a somewhat useful website full of a giant list of free workout videos: GenXNutrition. Whether anyone cares about staying fit… just sayin.

  42. get me there says:

    April 22nd, 2013 at 6:21 am (#)

    Hi, nice to meet you, get me there

  43. buyadildo.us says:

    May 17th, 2013 at 7:57 pm (#)

    You actually make it appear so easy along with your presentation but I in finding this matter to be really one thing which I feel I’d by no means understand. It sort of feels too complicated and very huge for me. I’m
    taking a look ahead for your next put up, I
    will try to get the hold of it!

  44. Best Way To Lose Weight - Fast Weight Loss says:

    July 10th, 2013 at 10:02 pm (#)

    We have master good quality products below. Undoubtedly selling price book-marking for revisiting. I personally shock that the ton try out you place to build this amazing helpful site.

  45. eMusic Review youtube says:

    July 29th, 2013 at 5:27 pm (#)

    Excellent post. I was checking constantly this blog and I am impressed!
    Very useful info specially the last part :) I care for such info a lot.
    I was looking for this certain information for
    a very long time. Thank you and best of luck.

  46. lose weight diet solution program says:

    August 1st, 2013 at 7:22 pm (#)

    I’m extremely impressed with your writing talents and also with the format on your weblog. Is that this a paid subject matter or did you customize it your self? Either way stay up the nice high quality writing, it’s uncommon to see a great weblog like this one nowadays.
    .

  47. www.bettingtipsrevealed.com says:

    August 2nd, 2013 at 4:15 am (#)

    Remember the excitement of watching the pounds drop one by one to unhealthy diets, fasts,
    very low-calorie diets, drugs, even gut-rearranging surgery.
    If you are trying to lose weight without Dieting On A College Budget.

    Having self-control is the key to avoiding holiday overindulgence and the futility of Dieting On A
    College Budget. Recent studies have revealed that eating soup
    can help you make your diet simpler, your exercise program simpler and
    cure type 2 diabetes it is something I enjoy doing more than the last time.

  48. cindy says:

    August 3rd, 2013 at 7:20 pm (#)

    Love this club promoting stuff.

  49. Visit Website says:

    August 5th, 2013 at 3:17 pm (#)

    Good day, Nice post. There’s a dilemma with all your site in world wide web adventurer, can test this kind of? IE ‘s still the market industry director plus a big component of men and women is going to omit your spectacular writing due to this challenge.

  50. псориаз это паразиты says:

    December 8th, 2013 at 4:39 am (#)

    Many thanks for several other insightful web page. Where by more can I am getting this kind of details coded in a real ideal style? I own a undertaking i’m simply at this point working away at, and i have also been at the peek out and about with regard to similarly info.

  51. Democracy institute says:

    January 30th, 2014 at 12:13 am (#)

    I stumbled across your page when I was look for notions for my next article. Your information was very informative. Please take a minute and visit my pagehttp://archive.sciencentral.com

  52. turmeric health benefits says:

    February 16th, 2014 at 3:30 pm (#)

    hello there and thank you for your info – I’ve certainly
    picked up anything new from right here. I did however expertise a few technical issues using this web site,
    since I experienced to reload the website lots of times previous to I could
    get it to load properly. I had been wondering if
    your web hosting is OK? Not that I’m complaining, but slow loading instances times will often affect your
    placement in google and can damage your high-quality
    score if advertising and marketing with Adwords. Well I
    am adding this RSS to my email and can look out for much more
    of your respective fascinating content. Make sure
    you update this again soon.

  53. fat loss diet says:

    April 29th, 2014 at 6:03 am (#)

    fat loss diet

    Bad Belly Fat | ScienCentral | Science Videos | Science News :: ScienCentral | Science Videos | Science News

  54. synergiezed business says:

    May 18th, 2014 at 4:31 pm (#)

    Good post. I learn something new and challenging on websites I stumbleupon on a daily basis.
    It’s always exciting to read content from other authors and practice a little something
    from their sites.

    my page: synergiezed business

  55. youtubemp3 says:

    June 25th, 2014 at 2:00 pm (#)

    Everything is very open with a really clear explanation of the issues.
    It was truly informative. Your site is extremely helpful.
    Thanks for sharing!

  56. related web page says:

    August 17th, 2014 at 11:38 am (#)

    hello there! , I love the publishing pretty a lot! promote we be in contact more around this page with Google? My partner and i require an experienced with this place to remedy my issue.. related web page May be that is anyone! Having a look ahead of time to look anyone.

  57. pernak pernik handphone says:

    March 17th, 2015 at 11:03 pm (#)

    Hi there to every body, it’s my first pay a quick visit of
    this website; this blog consists of amazing and actually excellent material for visitors.

  58. ト鉄部・木部用塗料建物用プラ says:

    September 2nd, 2015 at 9:57 pm (#)

    アイフォン6ケースFOR APPLE iP

  59. ナカキン新聞挟ワンタッチ式34 says:

    September 2nd, 2015 at 9:57 pm (#)

    ith Credit C

  60. webpage says:

    November 28th, 2017 at 3:35 pm (#)

    Thank you for some other informative website. The place else may just I get that kind of information written in such a perfect method? I have a venture that I am simply now running on, and I’ve been at the glance out for such info.

Leave a Response


Archives


Clicky Web Analytics